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MGluR5 Antibody (FITC)

CAT: 0013-GTR18028882Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18028882Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to mGluR1 (FITC) . The AMPA receptor is a non-NMDA-type ionotropic transmembrane receptor for glutamate that mediates fast synaptic transmission in the CNS. AMPARs are composed of four types of subunits, designated as GluR1, GluR2, GluR3 and GluR4, which combine to form tetramers..
Product Name Alternative
MGluR5, mGlu5, GRM5, GPRC1E, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 5 variant F, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, Glutamate receptor metabotropic 5, mGluR5a, mGluR5b, mGluR, Glutamate receptor metabotropic 1, mGlu1, mGluR1, GRM1, GRM 1, GRM1A, GRM1 alpha, GRM1_HUMAN, GPRC1A, Metabotropic glutamate receptor 1, mGluR1 alpha
UniProt
P31424
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Target
MGluR5
Clonality
Monoclonal
Clone
N75/33 (Formerly sold as S75-33)
Conjugation
FITC
Field of Research
Signal Transduction
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:1000), ICC/IF (1:100)
Molecular Weight
130kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of mGluR1/5 glutamate receptor in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
ICC, IF, IHC, IP, WB
NCBI Accession Number
NP_058708.1
Host or Source
Mouse
Preservative
640.91mM DMSO, 136.36 mM Ethanolamine, 126.89 mM chlorides, 9.09mM phosphates, 9.09mM NaHCO3
Isotype
IgG1
Entrez
24418

UniProtKB · P31424

Metabotropic glutamate receptor 5

GRM5_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P31424
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Grm5
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
mGluR5
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinMethylationPhosphoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

SignalTransmembraneTransmembrane helix

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