Recombinant Mouse Ccl24 Protein(Trx Tag)

Recombinant Mouse Ccl24 Protein(Trx Tag)

• Background: CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with an chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with an aspirin-exacerbated respiratory disease.
• Abbreviation: Ccl24
• Synonyms: C-C motif chemokine 24, CCL24, CCL24, Chemokine CC Motif Ligand 24, CK beta 6, CK-beta-6, Ckb6, Eosinophil chemotactic protein 2, Eotaxin-2, MPIF-2, MPIF2, Myeloid progenitor inhibitory factor 2, SCYA24, Small inducible cytokine subfamily A (Cys-Cys) member 24, Small-inducible cytokine A24
• CAS Number: 9000-83-3
• UniProt: Q9JKC0
• Accession Number: Q9JKC0
• Host: E. coli
• Origin Species: Mouse
• Tag: N-Trx
• Sequence: Val27-Val119
• Field of Research: Immunology
• Purity: > 90% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
• Molecular Weight: 33 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.