Products for Research Use Only

SHANK1 Antibody (APC)

CAT: 0013-GTR18028719Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18028719Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mouse monoclonal to SHANK1 (APC) . Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in specific cognitive processes, along with its importance for synapse structure and function in vivo..
Product Name Alternative
GKAP/SAPAP interacting protein, OTTHUMP00000174437, SH3 and multiple ankyrin repeat domains 1, SH3 and multiple ankyrin repeat domains protein 1, SH3/ankyrin domain gene 1, SHAN1_HUMAN, SHANK 1, Shank1, Shank1a, Somatostatin receptor interacting protein, Somatostatin receptor-interacting protein, SPANK 1, SPANK1, SSTR interacting protein, SSTR-interacting protein, SSTRIP, Synamon
UniProt
Q9WV48
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein amino acids 469-691 (SH3/PDZ domains) of rat Shank1
Target
SHANK1
Clonality
Monoclonal
Clone
N22/21 (Formerly sold as S22-21)
Conjugation
APC
Field of Research
Neuroscience
Purification
Protein G Purified
Concentration
1 mg/ml
Dilution
WB (1:1000), IHC (1:1000), ICC/IF (1:100)
Molecular Weight
190-220 kDa
Storage Conditions
Conjugated antibodies should be stored according to the product label
Notes
For research use only.
Applications Notes
1 μg/ml was sufficient for detection of Shank1 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Tested Applications
AM, IHC, WB
NCBI Accession Number
NP_113939.2
Host or Source
Mouse
Preservative
95.46mM Phosphate, 2.48mM MES and 2mM EDTA
Isotype
IgG1
Entrez
78957

UniProtKB · Q9WV48

SH3 and multiple ankyrin repeat domains protein 1

SHAN1_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
Q9WV48
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Shank1
Protein existence
1: Evidence at protein level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
Shank1
EC number
—
Processing
—
Secondary accessions
Q9QZZ8, Q9WU13, Q9WUE8
Protein keywords

Technical term

3D-structureReference proteome

Coding sequence diversity

Alternative splicing

Domain

ANK repeatRepeatSH3 domain

Cellular component

CytoplasmSynapse

Biological process

DifferentiationNeurogenesis

PTM

MethylationPhosphoprotein