LAR Antibody (HRP)

CAT: 0013-GTR18027666Size: 100 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR18027666Size:100 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Mouse monoclonal antibody to PTPRF (HRP) . PTPRF or leukocyte common antigen-related protein (LAR) is a widely expressed protein tyrosine phosphatase with an extracellular receptor region that resembles a cell adhesion molecule. PTPRF removes phosphate group from-catenin, an event that may subsequently facilitate cell-cell adhesion and ensure the stability of the cadherin complex. This phosphatase has also been implicated in various cellular processes such as neurite growth, nerve regeneration, actin remodeling and regulation of insulin function . Anti-PTPRF (C-terminal) antibody is specific for the extracellular and cytoplasmic subunits of human PTPRF (approx. 210, 150 and 85 kDa) . Detection of the PTPRF bands by immunoblotting is specifically inhibited by the immunizing peptide.

Product Name Alternative

PTPRF, LAR, Leukocyte antigen related, Leukocyte antigen related PTP receptor, Leukocyte antigen related tyrosine phosphatase, Leukocyte common antigen related, Receptor-type tyrosine-protein phosphatase F, Receptor type tyrosine protein phosphatase F precursor, Protein Tyrosine Phosphatase Receptor Type F, Protein tyrosine phosphatase receptor type F polypeptide, Receptor linked phosphatase LAR, LAR protein, LARS, LARFN5C, LCA homolog, FLJ43335, FLJ45062, FLJ45567

UniProt

P10586

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR. 97% identical in both rat and mouse. > 80% identity with PTPRD and PTPRS. > 50% identity with PTPRM and PTPRK.

Target

LAR

Clonality

Monoclonal

Clone

N165/38 (Formerly sold as S165-38)

Conjugation

HRP

Field of Research

Signal Transduction

Purification

Protein G Purified

Concentration

1 mg/ml

Dilution

WB (1:1000)

Molecular Weight

85kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of LAR/PTPRF in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Tested Applications

ICC, IF, WB

NCBI Accession Number

NP_002831.2

Host or Source

Mouse

Preservative

73.64mM Carbonate, 54.55mM Ethanolamine, 45.45mM Cyanoborohydride, 18.18mM Sodium Hydroxide 0.23mM Citrate

Isotype

IgG2a

Entrez

5792

UniProtKB · P10586

Receptor-type tyrosine-protein phosphatase F

PTPRF_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P10586
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PTPRF
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.1.3.48
Processing: Precursor
Secondary accessions: D3DPX6, D3DPX7, Q5T021, Q5T022, Q5W9G2, Q86WS0

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

PTM

Disulfide bondGlycoproteinPhosphoprotein

Molecular function

Heparin-bindingHydrolaseProtein phosphataseReceptor

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Related Products

Catalog	Name
GTR18080417	LAR Antibody
GTR17969572	Lar Antibody
GTR17857676	LAR Antibody
GTR18564117	LAR/PTPRF Rabbit Polyclonal Antibody (HRP)
GTR18027667	LAR Antibody (PerCP)
GTR18203827	LAR Polyclonal Antibody
GTR18048964-01	LAR Polyclonal Antibody
GTR18027668	LAR Antibody (RPE)
GTR17857677	LAR Antibody (PE)
GTR18027665	LAR Antibody (FITC)

Alternative Products

Catalog	Name
10R-P156a	HRP antibody
ARP68308_P050-HRP	FAM40A Antibody : HRP (ARP68308_P050-HRP)
OAPB00675-100UG-HRP	VPS53 Antibody : HRP (OAPB00675-HRP)
OAPB00667-100UG-HRP	RGP1 Antibody : HRP (OAPB00667-HRP)
OAPB00663-100UG-HRP	Ambra1 Antibody : HRP (OAPB00663-HRP)
OAPB00662-100UG-HRP	Ambra1 Antibody : HRP (OAPB00662-HRP)
OAPB00658-100UG-HRP	EVER1 Antibody : HRP (OAPB00658-HRP)
OAPB00640-100UG-HRP	LGI3 Antibody : HRP (OAPB00640-HRP)
OAPB00631-100UG-HRP	Slitrk5 Antibody : HRP (OAPB00631-HRP)
OAPB00628-100UG-HRP	SLITRK3 Antibody : HRP (OAPB00628-HRP)