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Mauritianin

CAT: 0804-HY-N5038-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N5038-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mauritianin is an orally active kaempferol glycoside. Mauritianin can be isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Mauritianin has hepatoprotective, neuroprotective, and renoprotective activities. Mauritianin increases vascular tone when used in combination with Alcesefoliside[2][3][4].
CAS Number
109008-28-8
UNSPSC
12352005
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mauritianin.html
Purity
99.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(O[C@H]2[C@@H]([C@H]([C@@H](O)[C@@H](CO[C@H]3[C@@H]([C@@H]([C@@H](O)[C@H](C)O3)O)O)O2)O)O[C@@]4([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O4)O)O)=C(C5=CC=C(O)C=C5)OC6=CC(O)=CC(O)=C61
Molecular Formula
C33H40O19
Molecular Weight
740.66
References & Citations
[1]Nahrstedt A, et al. Flavonoids from Acalypha indica. Fitoterapia. 2006 Sep;77 (6) :484-6.|[2]Ma J, et al. DNA topoisomerase I inhibitors from Rinorea anguifera. Bioorg Med Chem Lett. 2005 Feb 1;15 (3) :813-6.|[3]Kadinov B G, et al. In vitro effects of alcesefoliside and mauritianin, isolated from Astragalus monspessulanus subsp. monspessulanus, on the contractility of a. basilaris. Pharmacia, 2023, 70: 15-19. |[4]Manov V, et al. In vivo protective effects of Mauritianin. 2023.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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