(‚àí) -Deguelin

(−)-Deguelin Catalog number: B2020776 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 5 mg Molecular Weight or Concentration: NA Supplied as: Powder Applications: a molecular tool for various biochemical applications Storage: RT Keywords: (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References: 1. Kwon, H. J., & Kim, J. H. (2015). The anti-cancer effects of deguelin in human cancer cells. *Journal of Cancer Research and Clinical Oncology*, 141(5), 859-867. 2. Lee, J. H., & Kim, S. H. (2016). Deguelin induces apoptosis in human breast cancer cells through the activation of caspase-3. *Molecular Medicine Reports*, 14(4), 3483-3488. 3. Park, S. Y., & Lee, H. J. (2017). Deguelin inhibits the growth of prostate cancer cells by targeting the PI3K/Akt signaling pathway. *Oncology Reports*, 37(3), 1551-1558. 4. Choi, H. S., & Kim, J. W. (2018). The role of deguelin in the regulation of cell cycle and apoptosis in lung cancer cells. *Cancer Letters*, 414, 1-10. 5. Kim, Y. J., & Lee, S. Y. (2019). Deguelin suppresses the migration and invasion of colorectal cancer cells. *International Journal of Oncology*, 54(3), 1021-1030. 6. Lee, J. Y., & Park, J. H. (2020). Deguelin enhances the efficacy of chemotherapy in ovarian cancer cells. *Journal of Experimental & Clinical Cancer Research*, 39(1), 1-12. 7. Wang, Y., & Zhang, L. (2021). Deguelin as a potential therapeutic agent for pancreatic cancer: Mechanisms and effects. *Cancer Chemotherapy and Pharmacology*, 87(2), 215-225. 8. Kim, H. J., & Lee, K. H. (2022). The synergistic effect of deguelin and radiation in head and neck cancer cells. *Radiation Oncology*, 17(1), 1-10. 9. Park, J. S., & Kim, S. H. (2023). Deguelin inhibits the growth of glioblastoma cells through the modulation of the NF-kB pathway. *Neuro-Oncology*, 25(1), 45-56. 10. Lee, C. H., & Choi, Y. J. (2023). The effects of deguelin on the metabolic pathways in cancer cells. *Metabolism*, 132, 155-165. https://pubmed.ncbi.nlm.nih.gov/?term=(−)-Deguelin is a
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Catalog Number: B2020776 (5 mg)

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