GAL-021
CAT:
804-HY-101422-02
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GAL-021
- CAS Number: 1380341-99-0
- UNSPSC Description: GAL-021 is a potent BKCa-channel blocker. GAL-021 inhibits KCa1.1 in GH3 cells. GAL-021 is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 increases minute ventilation in rats and non-human primates[1][2].
- Target Antigen: Potassium Channel
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/GAL-021.html
- Purity: 99.93
- Solubility: DMSO : ≥ 30 mg/mL
- Smiles: CCCNC1=NC(N(OC)C)=NC(NCCC)=N1
- Molecular Weight: 254.33
- References & Citations: [1]Golder FJ, et al. Identification and Characterization of GAL-021 as a Novel Breathing Control Modulator. Anesthesiology. 2015 Nov;123(5):1093-104.|[2]J F McLeod, et al. GAL-021, a new intravenous BKCa-channel blocker, is well tolerated and stimulates ventilation in healthy volunteers. Br J Anaesth. 2014 Nov;113(5):875-83.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported