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RW3

CAT: 0804-HY-P10281-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10281-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RW3 (MP196) is a small cationic antimicrobial hexapeptide. RW3 targets the bacterial cytoplasmic membrane and inhibits cellular respiration and cell wall synthesis. RW3 exhibits high bioactivity against Gram-positive bacteria such as Bacillus subtilis 168 (MIC of 2 µg/mL) . RW3 causes shrinking of murine erythrocytes. RW3 can be used in antimicrobial and antifungal research[1].
CAS Number
359632-11-4
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/rw3.html
Purity
98.00
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N
Molecular Formula
C51H69N19O6
Molecular Weight
1044.22
References & Citations
[1]Wenzel M, et al. Towards profiles of resistance development and toxicity for the small cationic hexapeptide RWRWRW-NH2[J]. Frontiers in Cell and Developmental Biology, 2016, 4: 86.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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