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3-Hydroxypicolinic acid

CAT: 0804-HY-Y0030-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0030-01Size:500 mg
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Description
3-Hydroxypicolinic acid is a matrix. 3-Hydroxypicolinic acid coordinates with metal ions such as copper to form complexes with cytotoxic and antimycobacterial activity. 3-Hydroxypicolinic acid is used for the analysis of oligodeoxynucleotides in matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) . 3-Hydroxypicolinic acid is useful for nucleic acid analysis and anti-tuberculosis compound development[1][2][3].
CAS Number
874-24-8
Product Name Alternative
3-hydroxypyridine-2-carboxylic acid
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents; Drug Intermediate
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/3-Hydroxypicolinic_acid.html
Purity
99.92
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=NC=CC=C1O)O
Molecular Formula
C6H5NO3
Molecular Weight
139.11
Precautions
H315, H319, H335
References & Citations
[1]Zhou L, et al. A mixed matrix of 3-hydroxypicolinic acid and pyrazinecarboxylic acid for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of oligodeoxynucleotides. Rapid Commun Mass Spectrom. 2004;18 (7) :787-94.|[2]Brockman FJ, et al. Isolation and characterization of quinoline-degrading bacteria from subsurface sediments. Appl Environ Microbiol. 1989 Apr;55 (4) :1029-32.|[3]do Couto Almeida J, et al. Synthesis, cytotoxic and antitubercular activities of copper (II) complexes with heterocyclic bases and 3-hydroxypicolinic acid. Inorganica Chimica Acta, 2016, 446: 87-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite