[MePhe7]-Neurokinin B

[MePhe7]-Neurokinin B

• CAS Number: 110880-53-0
• UNSPSC Description: [MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC50 value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R)[1].
• Target Antigen: Neurokinin Receptor
• Type: Peptides
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/mephe7-neurokinin-b.html
• Purity: 98.87
• Solubility: DMSO : 20 mg/mL (ultrasonic)
• Smiles: CC(C[C@H](NC(CNC([C@@H](N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CCSC)=O)CC1=CN=CN1)=O)CC(O)=O)=O)CC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)C)CC4=CC=CC=C4)=O)=O)C(N[C@H](C(N)=O)CCSC)=O)C
• Molecular Weight: 1272.49
• References & Citations: [1]Misu R, et, al. Structure-activity relationship study of tachykinin peptides for the development of novel neurokinin-3 receptor selective agonists. Bioorg Med Chem. 2013 Apr 15;21(8):2413-2417.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported