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2-Chlorobenzimidazole

CAT: 0804-HY-W015575-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W015575-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Chlorobenzimidazole is a pharmaceutical intermediate used in the synthesis of a series of derivatives with anti-human cytomegalovirus (HCMV) activity. 2-Chlorobenzimidazole can be used to form metal complexes (cobalt, copper, and zinc), with zinc complexes exhibiting significant anticancer activity[1][2].
CAS Number
4857-06-1
UNSPSC
12352200
Hazard Statement
H315, H319, H335
Target
Drug Intermediate
Type
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-chlorobenzimidazole.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=NC2=CC=CC=C2N1
Molecular Formula
C7H5ClN2
Molecular Weight
152.58
Precautions
H315, H319, H335
References & Citations
[1]Zou R, Drach JC, Townsend LB. Design, synthesis, and antiviral evaluation of 2-chloro-5,6-dihalo-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections. J Med Chem. 1997 Feb 28;40 (5) :811-8. |[2]Sánchez-Guadarrama O, et al. Cytotoxic activity, X-ray crystal structures and spectroscopic characterization of cobalt (II), copper (II) and zinc (II) coordination compounds with 2-substituted benzimidazoles. J Inorg Biochem. 2009 Sep;103 (9) :1204-13.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported