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Melanotan I

CAT: 0804-HY-N2466-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2466-01Size:1 mg
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Description
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction[1][2][3][4].
CAS Number
75921-69-6
Product Name Alternative
MT-I; [Nle4, D-Phe7]-α-MSH
UNSPSC
12352209
Hazard Statement
H302, H312, H332
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Melanotan_I.html
Purity
99.09
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 50 mg/mL
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@H](CO)NC(C)=O)=O)C(N[C@@H](CO)C(N[C@@H](CCCC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CN=CN2)C(N[C@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(N)=O)C(C)C)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C78H111N21O19
Molecular Weight
1646.85
Precautions
H302, H312, H332
References & Citations
[1]Langan EA, et al. Melanotropic peptides: more than just 'Barbie drugs' and 'sun-tan jabs'? Br J Dermatol. 2010 Sep;163 (3) :451-5.|[2]Mahiques-Santos L. Melanotan [Melanotan]. Actas Dermosifiliogr. 2012 May;103 (4) :257-9. Spanish. |[3]Hadley ME, et al. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. 2006 Apr;27 (4) :921-30.|[4]Hadley ME, et al. Discovery and development of novel melanogenic drugs. Melanotan-I and -II. Pharm Biotechnol. 1998;11:575-95.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Launched
Isoform
MC1R

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