APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [PSH04-90]

APP/β-Amyloid Recombinant Rabbit Monoclonal Antibody [PSH04-90]

• Description: Amyloid beta precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein existing as several isoforms. The amino acid sequence of APP contains the amyloid domain (A-beta), which can be released by a two-step proteolytic cleavage. It is expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. APP acts as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is also involved in cell mobility and transcription regulation through protein-protein interactions.
• Product Name Alternative: A4 amyloid protein antibody A4_HUMAN antibody AAA antibody ABETA antibody ABPP antibody AD1 antibody AICD-50 antibody AICD-57 antibody AICD-59 antibody AID (50) antibody AID (57) antibody AID (59) antibody Alzheimer disease amyloid protein antibody Amyloid beta (A4) precursor protein antibody Amyloid beta A4 protein antibody Amyloid beta protein antibody Amyloid intracellular domain 50 antibody Amyloid intracellular domain 57 antibody Amyloid intracellular domain 59 antibody Amyloid precursor protein antibody APP antibody APPI antibody Beta amyloid peptide antibody beta-amyloid peptide antibody Beta-amyloid precursor protein antibody Beta-APP40 antibody Beta-APP42 antibody C31 antibody Cerebral vascular amyloid peptide antibody CTFgamma antibody CVAP antibody Gamma-CTF (50) antibody Gamma-CTF (57) antibody Gamma-CTF (59) antibody peptidase nexin II antibody peptidase nexin-II antibody PN 2 antibody PN II antibody PN-II antibody PN2 antibody PreA4 antibody Protease nexin II antibody Protease nexin-II antibody S-APP-alpha antibody S-APP-beta antibody sAPP antibody
• Abbreviation: APP, A4, AD1
• CAS Number: 9000-83-3
• Swiss Prot: P05067 Human, P12023 Mouse
• Cellular Locus: Cell membrane, Membrane, Perikaryon, Cell projection, growth cone, Membrane, clathrin-coated pit, Early endosome, Cytoplasmic vesicle.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within C-terminal human Amyloid Beta.
• Isotype: IgG
• Clone: PSH04-90
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P
• Positive Control: HeLa cell lysate, HeLa treated with 100ng/mL Nocodazole for 17 hours cell lysate, SH-SY5Y cell lysate, AD mouse brain tissue lysate, mouse brain tissue lysate, HeLa, AD mouse brain tissue, mouse brain tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:200-1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 87 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes