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Regaloside B

CAT: 0804-HY-N7688-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N7688-01Size:5 mg
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Description
Regaloside B is a phenylpropane. Regaloside B can be isolated from Lilium longiflorum. Regaloside B can inhibit the expression of VCAM-1, iNOS, and COX-2, with a p-p65/p-65 ratio. Regaloside B inhibits the mRNA of various chemokines and angiogenic factors (CXCL9, CXCL10, IL8, IDO) . Regaloside B has anti-inflammatory activity. Regaloside B can be used for osteogenic differentiation research[1][2][3].
CAS Number
[114420-67-6]
UNSPSC
12352005
Target
COX; CXCR; Indoleamine 2,3-Dioxygenase (IDO) ; Interleukin Related; NF-κB; NO Synthase
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Endocrinology; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/regaloside-b.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1O[C@H](COC(/C=C/C2=CC=C(O)C=C2)=O)COC(C)=O
Molecular Formula
C20H26O11
Molecular Weight
442.41
References & Citations
[1]Thi NN, et, al. Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities. Applied Biological Chemistry. 2017; 60: 527–533.|[2]Kim BR, et, al. Purification of Phenylpropanoids from the Scaly Bulbs of Lilium Longiflorum by CPC and Determination of Their DPP-IV Inhibitory Potentials. ACS Omega. 2020 Feb 20; 5 (8) : 4050-4057.|[3]Chen G, et al. Total Glycosides and Regaloside B from Lily: Potential Therapeutic Agents for Osteogenic Differentiation, Migration, and Angiogenesis. ACS Omega. 2025 Jul 20;10 (29) :31638-31648.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2; iNOS

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