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Ralitoline

CAT: 0804-HY-106747Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106747Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ralitoline is a sodium channel blocker with IC50 of 2 μM. Ralitoline has anticonvulsant activity[1][2].
CAS Number
93738-40-0
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ralitoline.html
Solubility
10 mM in DMSO
Smiles
CC(C=CC=C1Cl)=C1NC(/C=C2N(C(CS/2)=O)C)=O
Molecular Formula
C13H13ClN2O2S
Molecular Weight
296.77
References & Citations
[1]Löscher W, et al. Ralitoline: a reevaluation of anticonvulsant profile and determination of "active" plasma concentrations in comparison with prototype antiepileptic drugs in mice. Epilepsia. 1991 Jul-Aug;32 (4) :560-8.|[2]Rock DM, et al. Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro. Epilepsy Res. 1991 Apr;8 (3) :197-203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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