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IM176OUT05

CAT: 0804-HY-125283-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125283-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IM176OUT05 (2-Me-Phen hydrochloride), a biguanide, is a mitochondrial OXPHOS inhibitor. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process[1].
CAS Number
1643659-96-4
Product Name Alternative
2-Me-Phen (hydrochloride) ; 2-Me-Phenformin (hydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Mitochondrial Metabolism; Oxidative Phosphorylation
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/im176out05.html
Purity
99.43
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC(NC(NCCC1=CC=CC=C1C)=N)=N.Cl
Molecular Formula
C11H18ClN5
Molecular Weight
255.75
Precautions
H302, H315, H319, H335
References & Citations
[1]Son MJ, et al. A novel and safe small molecule enhances hair follicle regeneration by facilitating metabolic reprogramming. Exp Mol Med. 2018 Dec 6;50 (12) :1-15.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
M27989-01IM176OUT05

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