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(Z)-Guggulsterone

CAT: 0026-B2773-25Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2773-25Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(Z)-Guggulsterone is a synthetic form of the guggul tree plant steroid that displays an ability to lower LDL cholesterol and triglyceride levels. Acts as a selective antagonist of farnesoid X receptor (FXR) and inhibits FXR transactivation (IC50 = 10 µM in the presence of 100 µM chenodeoxycholic acid). Does not activate or inhibit transactivation of liver X receptor α (LXRα), peroxisome proliferator activated receptor γ (PPARγ), or retinoid X receptor α (RXRα).
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36months

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