Psoralenoside

CAT: 0804-HY-N7503-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N7503-01Size:5 mg
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Description
Psoralenoside is a benzofuran glycoside from Psoralea corylifolia[1]. Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol) [2]. Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity[3].
CAS Number
[905954-17-8]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Calcium Channel; Calmodulin; Histamine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/psoralenoside.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C\C1=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C=C(OC=C3)C3=C1
Molecular Formula
C17H18O9
Molecular Weight
366.32
Precautions
H315, H319
References & Citations
[1]Chun-Feng Qiao, et al.Psoralenoside and isopsoralenoside, two new benzofuran glycosides from Psoralea corylifolia. Chem Pharm Bull (Tokyo) . 2006 May;54 (5) :714-6.|[2]Muhammad Bilal Riaz, et al. Pharmacological and computational evaluation of fig for therapeutic potential in hyperactive gastrointestinal disorders. BMC Complement Altern Med. 2019 Dec 3;19 (1) :348.|[3]Yue-Fei Wang, et al.A UPLC-MS/MS method for in vivo and in vitro pharmacokinetic studies of psoralenoside, isopsoralenoside, psoralen and isopsoralen from Psoralea corylifolia extract. J Ethnopharmacol
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
H1 Receptor; L-type calcium channel

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CatalogName
RM-P191500-01Psoralenoside
M38748-01Trans-Psoralenoside

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