Recombinant Human IL-28B/IFN-lambda-3 protein (His tag)

Recombinant Human IL-28B/IFN-lambda-3 protein (His tag)

• Background: Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
• Abbreviation: IL-28B;IFN-lambda-3
• Synonyms: Cytokine Zcyto, ZCYTO, IFNL3, IFN-lambda-3, IFN-lambda-4, IL-28B, IL-28C, IL28B, IL28C, Cytokine Zcyto22, IFNL4, IFN-lambda 3, interferon lambda 3, Interferon Lambda-3, Interferon Lambda-4, Interleukin-28B, Interleukin-28C, ZCYTO22
• CAS Number: 9000-83-3
• UniProt: Q8IZI9
• Accession Number: Q8IZI9
• Host: E. coli
• Origin Species: Human
• Tag: N-His
• Sequence: Val 22-Val 196
• Field of Research: Signal Transduction;Microbiology;immunology
• Purity: > 95% as determined by reducing SDS-PAGE.
• Bioactivity: Not validated for activity
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
• Molecular Weight: 25 kDa
• Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
• Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.