Sarglaroids F

• UNSPSC Description:

  Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1(P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells[1].

• Target Antigen:

  Caspase

• Type:

  Natural Products

• Related Pathways:

  Apoptosis

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/sarglaroids-f.html

• Solubility:

  10 mM in DMSO

• Smiles:

  [H][C@@]1([C@](O)(COC(/C(C)=C/C)=O)[C@H]2C[C@H]2[C@@]1([C@]([C@H]3O)([C@@]4([C@@]5([H])/C(C([C@H](O)[C@@]6(C)[C@H]7[C@H](C7)C3=C65)=O)=C(C)/C(OC)=O)O8)[H])C)CC4=C(COC(C)=O)C8=O

• Molecular Weight:

  692.75

• References & Citations:

  [1]Sun Y, et al. Anti-Inflammatory Lindenane Sesquiterpenoid Dimers from the Roots of Sarcandra glabra. J Agric Food Chem. 2023 Sep 13.. .

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported