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Sarglaroids F

CAT: 0804-HY-N12235Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N12235Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sarglaroids F (compound 6) is an anti-inflammatory agent isolated from the roots of Grass Coral. Sarglaroids F inhibits LPS/ATP-induced IL-1β release by affecting K+ efflux and reducing Caspase-1 (P20) levels. Sarglaroids F is not cytotoxic to RAW264.7 cells[1].
UNSPSC
12352005
Target
Caspase
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sarglaroids-f.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]1([C@](O)(COC(/C(C)=C/C)=O)[C@H]2C[C@H]2[C@@]1([C@]([C@H]3O)([C@@]4([C@@]5([H])/C(C([C@H](O)[C@@]6(C)[C@H]7[C@H](C7)C3=C65)=O)=C(C)/C(OC)=O)O8)[H])C)CC4=C(COC(C)=O)C8=O
Molecular Formula
C38H44O12
Molecular Weight
692.75
References & Citations
[1]Sun Y, et al. Anti-Inflammatory Lindenane Sesquiterpenoid Dimers from the Roots of Sarcandra glabra. J Agric Food Chem. 2023 Sep 13.. .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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