Allopregnanolone

• Background:

  Allopprenanolone is a natural metabolite of progesterone that is devoid of any progestational activity. It acts and functions as a potent ligand of GABA type A receptor complexes in the CNS. It is a neuroactive steroid. Has recently been approved as a drug for postpartum depression by the FDA.

• Description:

  Positive allosteric modulator of GABAA receptors

• Product Name Alternative:

  (3α,5α) -3-Hydroxy-pregnan-20-one; (3α,5α) -tetrahydroprogesterone; 3-OH-DHP

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Neuroscience

• Purity:

  >98% (HPLC) ; NMR (Conforms)

• Weight:

  0.005

• Format:

  White to off-white powder

• Solubility:

  May be dissolved in DMSO (32 mg/ml); or Ethanol (32 mg/ml)

• Molecular Formula:

  C21H34O2

• Molecular Weight:

  318.5

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• CAS Number:

  516-54-1