Rucaparib phosphate
CAT:
400-SIH-580-5MG
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rucaparib phosphate
- Background: Rucaparib is a PARP1, PARP2 and PARP3 inhibitor and inhibits PARP-mediated DNA repair (1). It is being developed for ovarian, prostate and bladder cancers (2, 3).
- Description: PARP Inhibitor
- Product Name Alternative: 8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one, phosphate; AG-14699; PF01367338
- CAS Number: 459868-92-9
- UNSPSC: 41116105
- Source: Synthetic
- Purity: >98% (HPLC); NMR (Conforms)
- Weight: 0.005
- Format: Yellow powder
- Solubility: May be dissolved in DMSO (25 mg/ml)
- Molecular Formula: C19H18FN3O * H3PO4
- Molecular Weight: 421.4
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- References & Citations: 1. https://pubchem.ncbi.nlm.nih.gov/compound/rucaparib 2. Dockery L.E., Gunderson C.C., and Moore K.N. (2017) Onco Target Ther. 10: 3029-3037. 3. Syed Y.Y. (2017) Drugs. 77(5): 585-592.