Baicalein

• Background:

  Baicalein is a flavonoid that is positive allosteric modulator of the GABA A Receptor (1). It also inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils (2).

• Description:

  Lipoxygenase inhibitor

• Product Name Alternative:

  5,6,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one; Biacalein

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis | Cell Cycle | Neuroscience | Neurodegeneration | Alzheimer's Disease | Parkinson's Disease

• Purity:

  >98% (TLC) ; NMR (Conforms)

• Weight:

  0.005

• Format:

  Yellow to Yellow-green Crystalline powder

• Solubility:

  May be dissolved in DMSO (15 mg/ml)

• Molecular Formula:

  C15H10O5

• Molecular Weight:

  270.2

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Zhang S.Q., et al. (2013) J Neurosci. Res. 91(9): 1239-1246. 2. Zhu M., et al. (2004) J Biol Chem. 279(26): 26846-26857.

• CAS Number:

  491-67-8