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Terazosin

CAT: 0400-SIH-516-100MGSize: 100 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-516-100MGSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Terazosin (TZ) which is marketed as an alpha1-adrenergic receptor antagonist, has been shown to alleviate organ damaged and increase survival in rodent models of sepsis and stroke in vivo (1). It inhibits apoptosis in macrophages by activation of Pgk1 and Hsp90 (1).
Description
Alpha adrenergic antagonist, and Hsp90 Activator
CAS Number
63074-08-8
Product Name Alternative
1- (4-Amino-6,7-dimethoxy-2-quinazolinyl) -4-[ (tetrahydro-2-furanyl) carbonyl]piperazine
UNSPSC
41116105
Type
Antagonist
Source
Synthetic
Field of Research
Cancer | Apoptosis | Neuroscience | Neurotransmitter Receptors | Alpha-2 Adrenergic Receptors
Purity
>98%
Weight
0.1
Format
White to off-white solid
Solubility
Soluble to 20mg/ml in warm water
Molecular Formula
C19H25N5O4·HCl
Molecular Weight
423.89
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Chen X., et al. (2015) Nature Chem Biol. 11:19-25. 2. Hancock A.A., et al. (1995) J Recept Signal Transduct Res. 15: 863. 3. Kyncl J.J. (1986) Am J Med. 80:12.

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