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Ruxolitinib

CAT: 0400-SIH-509-25MGSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-509-25MGSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ruxolitinib is a Janus-associated kinases (JAK) inhibitor, which specifically inhibits JAK1 and JAK3. JAKs are known to active the signaling of certain growth factor receptors and cytokines.
Description
JAK kinase inhibitor
CAS Number
941678-49-5
Product Name Alternative
(3R) -3- (4- (7H-pyrrolo[2,3-d]pyrimidin-4-yl) -1H-pyrazol-1-yl) -3-cyclopentylpropanenitrile
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>98%
Weight
0.025
Format
Off-white solid
Solubility
Soluble in DMSO (25 mg/ml) or EtOH (~15 mg/ml)
Molecular Formula
C17H18N6
Molecular Weight
306.4
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Aittomäki S., & Pesu M. (2014) Basic & Clin. Pharm.Toxic. 114(1): 18–23.

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RM-R241201-01Ruxolitinib Impurity A (Ruxolitinib Enantiomer)
T1829-01Ruxolitinib

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