PMA

• Background :

  PMA (Phorbol 12-myristate 13-acetate) is a phorbol ester. It is used experimentally as a reversible protein kinase C (PKC) activator. It has been shown to be a potent tumor promoter.

• Description :

  Protein Kinase C Activator

• CAS Number :

  16561-29-8

• Product Name Alternative :

  Phorbol 12-myristate 13-acetate

• UNSPSC :

  41116105

• Type :

  Activator

• Source :

  Synthetic

• Field of Research :

  Cell Signaling

• Purity :

  ≥99% (TLC)

• Weight :

  0.005

• Format :

  Colorless amorphous film or foam

• Solubility :

  Soluble in DMSO (25 mg/ml), 100% ethanol (25 mg/ml), acetone, ether or dimethyl formamide; almost insoluble in aqueous buffers

• Molecular Formula :

  C36H58O8

• Molecular Weight :

  616.8

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Murphy T. V., Prountzos C., Kotsonis P., Iannazzo L., & Majewski H. (1999). Euro.J. Pharm. 381(1): 77–84. 2. Castagna M., et al. (1982) J. Biol. Chem. 257(13): 7847–7851.