PMA

• Background:

  PMA (Phorbol 12-myristate 13-acetate) is a phorbol ester. It is used experimentally as a reversible protein kinase C (PKC) activator. It has been shown to be a potent tumor promoter.

• Description:

  Protein Kinase C Activator

• Product Name Alternative:

  Phorbol 12-myristate 13-acetate

• UNSPSC:

  41116105

• Type:

  Activator

• Source:

  Synthetic

• Field of Research:

  Cell Signaling

• Purity:

  ≥99% (TLC)

• Weight:

  0.001

• Format:

  Colorless amorphous film or foam

• Solubility:

  Soluble in DMSO (25 mg/ml), 100% ethanol (25 mg/ml), acetone, ether or dimethyl formamide; almost insoluble in aqueous buffers

• Molecular Formula:

  C36H58O8

• Molecular Weight:

  616.8

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Murphy T. V., Prountzos C., Kotsonis P., Iannazzo L., & Majewski H. (1999). Euro.J. Pharm. 381(1): 77–84. 2. Castagna M., et al. (1982) J. Biol. Chem. 257(13): 7847–7851.

• CAS Number:

  16561-29-8