Products for Research Use Only

Pazopanib

CAT: 0400-SIH-506-5MGSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-506-5MGSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pazopanib is a multi-tyrosine kinase inhibitor. It was approved by the US Food and Drug Administration in 2009. Pazopanib exerted antitumor effects through the inhibition of HGF/c-MET signaling.
Description
Tyrosine kinase inhibitor
CAS Number
444731-52-6
Product Name Alternative
5-[[4-[ (2,3-dimethyl-2H-indazol-6-yl) methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>98%
Weight
0.005
Format
White solid powder
Solubility
Soluble in DMSO, not in water
Molecular Formula
C21H23N7O2S
Molecular Weight
437.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Outani H., et al. (2014) BMC Cancer. 14: 455. 2. Pick A.M., & Nystrom K.K. (2012) Clin. Ther. 34(3): 511–520.

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