Dovitinib

• Background:

  Dovitinib is a potent growth factor receptor kinase inhibitor with effects against FLT-3, c-KIT, VEGFR, PDGFRß and CSF-1R.

• Description:

  FGFR3 inhibitor

• Product Name Alternative:

  4-​​amino-​​5-​​fluoro-​​3-​​[6-​​ (4-​​methyl-​​1-​​piperazinyl) ​-​​1H-​​benzimidazol-​​2-​​yl]​-​2 (1H) ​-​​quinolinone

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling

• Purity:

  ≥98%

• Weight:

  0.005

• Format:

  Crystalline solid

• Solubility:

  Soluble in DMSO

• Molecular Formula:

  C21H21FN6O

• Molecular Weight:

  392.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Konecny G.E., et al. (2013) Mol. Cancer Ther. 12(5): 632–642.

• CAS Number:

  405169-16-6