BRD 7389

• Background:

  BRD 7389 is a p90 ribosomal S6 kinase (RSK) inhibitor. Specifically, BRD7398 inhibits RSK1, RSK2 and RSK3. This compound has been seen to unregulate insulin expression in terminally differentiated pancreatic &alpha-cells.

• Description:

  P90 RSK kinase inhibitor

• Product Name Alternative:

  BRD7389, BRD-7389, 1-[ (2-Phenylethyl) amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione, 1-Phenethylamino-3H-naphtho[1,2,3-de]quinoline-2,7-dione

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (HPLC)

• Weight:

  0.025

• Format:

  Orange powder

• Solubility:

  Soluble to 100 mM in DMSO

• Molecular Formula:

  C24H18N2O2

• Molecular Weight:

  366.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Fomina-Yadlin D., et al. (2010) Pro. Nat. Acad.Sci. USA. 107(34): 15099–15104.

• CAS Number:

  376382-11-5