AZD6244

CAT: 0400-SIH-495-5MGSize: 5 mgDry Ice: NoHazardous: No

CAT#:0400-SIH-495-5MGSize:5 mg

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Background

AZD6244 is a MEK-1 inhibitor. Specifically, AZD6244 inactivates the phosphorylation of ERK1/2.

Description

ERK kinase inhibitor

CAS Number

606143-52-6

Product Name Alternative

Selumetinib, AZD6244, 6- (4-bromo-2-chloroanilino) -7-fluoro-N- (2-hydroxyethoxy) -3-methylbenzimidazole-5-carboxamide

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥98%

Weight

0.005

Format

White to off-white solid

Solubility

Soluble in DMSO (92 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C)

Molecular Formula

C17H15BrClFN4O3

Molecular Weight

457.7

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Haasbach E., Hartmayer C., & Planz O. (2013) Antiviral Research. 98(2): 319–324.

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