AR A014418

• Background :

  AR A014418 is a highly selective glycogen synthase kinase 3 (GSK-3) inhibitor. GSK-3 is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer′s disease. AR A014418 is cell permeable.

• Description :

  GSK-3 kinase inhibitor

• Product Name Alternative :

  N- (4-Methoxybenzyl) -N′- (5-nitro-1,3-thiazol-2-yl) urea

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥95% (HPLC)

• Weight :

  0.005

• Format :

  White to off-white solid

• Solubility :

  Soluble in DMSO, methanol, 100% ethanol or ethyl acetate

• Molecular Formula :

  C12H12N4O4S

• Molecular Weight :

  308.3

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Bhat R.V., & Budd S.L. (2002) Neuro-Signals. 11(5): 251–261. 2. Gould T.D., Einat H., Bhat R., & Manji H.K. (2004) Int. J. Neuropsychopharmacology (CINP). 7(4): 387–390.

• CAS Number :

  487021-52-3