Y 27632

• Background:

  Y 27632 is a very potent and selective ROCK1 and ROCK2 inhibitor. Y 27632 is cell permeable and is an ATP competitive inhibitor.

• Description:

  ROCK kinase inhibitor

• Product Name Alternative:

  Y-27632 dihydrochloride, (R) - (+) -trans-N- (4-Pyridyl) -4- (1-aminoethyl) -cyclohexanecarboxamide . 2HCl

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (HPLC)

• Weight:

  0.005

• Format:

  White to pale yellow powder

• Solubility:

  Soluble in DMSO (25 mg/ml), methanol (25 mg/ml), acetonitrile (<1 mg/ml), dioxan (<1 mg/ml), water (very soluble

• Molecular Formula:

  C14H23Cl2N3O

• Molecular Weight:

  320.3

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Shi J., et al. (2013) Cell Death & Disease, 4: e483.

• CAS Number:

  146986-50-7