Vandetanib

• Background:

  Vandetanib is a specific inhibitor of Flk-1 and Flt-4.

• Description:

  VEGFR inhibitor

• Product Name Alternative:

  N- (4-bromo-2-fluorophenyl) -6-methoxy-7-[ (1-methylpiperidin-4-yl) methoxy]quinazolin-4-amine

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cardiovascular System | Cancer Growth Inhibitors | Growth Factor Receptor Inhibitors

• Purity:

  ≥98% (HPLC)

• Weight:

  0.01

• Format:

  Yellow solid

• Solubility:

  Soluble in DMSO (30 mg/ml) or EtOH (10 mg/ml)

• Molecular Formula:

  C22H24BrFN4O2

• Molecular Weight:

  475.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Bruns C.J., et al. (2000) Clin. Cancer. Res: J. Am. Assoc. Cancer Res. 6(5): 1936–1948.

• CAS Number:

  443913-73-3