SU 4312

• Background :

  SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases, including VEGFR-2 (Flk-1, KDR).

• Description :

  VEGFR, PDGFR kinase inhibitor

• Product Name Alternative :

  3-[[4- (dimethylamino) phenyl]methylene]-1,3-dihydro-2H-indol-2-one

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cardiovascular System | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥98% (HPLC)

• Weight :

  0.005

• Format :

  Orange solid

• Solubility :

  Soluble in DMSO (25 mg/ml)

• Molecular Formula :

  C17H16N2O

• Molecular Weight :

  264.3

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Zaman G.J., et al. (1999) Biochem. Pharm. 57(1): 57–64. 2. Shimotake J., Derugin N., Wendland M., Vexler Z.S., & Ferriero D.M. (2010) Stroke. 41(2): 343–349. 3. Schultheiss C., et al. (2006) Angiogenesis. 9(2): 59–65.

• CAS Number :

  5812-07-7