Sorafenib

• Background:

  Sorafenib display inhibition of multiple kinase targets including, VEGFR, PDGFR, and Raf.

• Description:

  Raf-1 kinase inhibitor

• Product Name Alternative:

  4-[4-[[4-chloro-3- (trifluoromethyl) phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; 4-methylbenzenesulfonic acid

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling

• Purity:

  >99%

• Weight:

  0.01

• Format:

  Off white powder

• Solubility:

  Soluble inDMSO (200mg/ml) or ethanol (3mg/ml)

• Molecular Formula:

  C21H16ClF3N4O3

• Molecular Weight:

  464.8

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Juan, L., et al. (2014) Environmental Toxic. Pharm. 38(2): 438–443.

• CAS Number:

  284461-73-0