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Lestaurtinib

CAT: 0400-SIH-460-1MGSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-460-1MGSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lestaurtinib is potent JAK2, FLT3 and TrkA receptor tyrosine kinase inhibitor. Specifically, it prevents STAT5 phosphorylation. Lestaurtinib exhibits antiproliferative activity in vitro.
Description
FLT3, TrkA kinase inhibitor
CAS Number
111358-88-4
Product Name Alternative
KT5555, CEP-701, (9S,10S,12R) -2,3,9,10,11,12-Hexahydro-10-hydroxy-10- (hydroxymethyl) -9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
≥98% (HPLC)
Weight
0.001
Format
White powder
Solubility
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Molecular Formula
C26H21N3O4
Molecular Weight
439.5
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Weisel K.C., et al. (2007) Ann. NY Acad. Sci. 1106: 190–196. 2. Hexner E.O., et al. (2008) Blood. 111(12): 5663–5671.

Alternative Products

CatalogName
A4513-5Lestaurtinib

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