JX 401

• Background :

  JX 401 is a potent and reversible inhibitor of p38α. Specifically, it binds MAPK p38α. JX 401 is cell permeable.

• Description :

  P38 MAP kinase inhibitor

• Product Name Alternative :

  1-[2-Methoxy-4- (methylthio) benzoyl]-4- (phenylmethyl) piperidine

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥98% (TLC)

• Weight :

  0.05

• Format :

  Off-white solid

• Solubility :

  Soluble in DMSO (20 mg/ml) or ethanol (10 mg/ml)

• Molecular Formula :

  C21H25NO2S

• Molecular Weight :

  355.5

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Friedmann Y., et al. (2006) Mol. Pharm. 70(4): 1395–1405.

• CAS Number :

  349087-34-9