JX 401

• Background:

  JX 401 is a potent and reversible inhibitor of p38α. Specifically, it binds MAPK p38α. JX 401 is cell permeable.

• Description:

  P38 MAP kinase inhibitor

• Product Name Alternative:

  1-[2-Methoxy-4- (methylthio) benzoyl]-4- (phenylmethyl) piperidine

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (TLC)

• Weight:

  0.01

• Format:

  Off-white solid

• Solubility:

  Soluble in DMSO (20 mg/ml) or ethanol (10 mg/ml)

• Molecular Formula:

  C21H25NO2S

• Molecular Weight:

  355.5

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Friedmann Y., et al. (2006) Mol. Pharm. 70(4): 1395–1405.

• CAS Number:

  349087-34-9