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Gefitinib

CAT: 0400-SIH-445-50MGSize: 50 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-445-50MGSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gefitinib is a selective inhibitor of EGFR tyrosine kinase by blocking EGFR autophosphorylation.
Description
EGFR Kinase inhibitor
CAS Number
184475-35-2
Product Name Alternative
N- (3-chloro-4-fluorophenyl) -7-methoxy-6- (3-morpholin-4-ylpropoxy) quinazolin-4-amine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>99%
Weight
0.05
Format
Solid
Solubility
Soluble in DMSO (89 mg/ml at 25 °C), methanol (20 mg/ml), ethanol (4 mg/ml at 25 °C), DMF (20 mg/ml), and water (<1 mg/ml at 25 °C)
Molecular Formula
C22H24ClFN4O3
Molecular Weight
446.9
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Ciardiello F., et al. (2000) Clin. Cancer Res. 6(5): 2053–2063.

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