Doramapimod

• Background :

  Doramapimod is a highly potent and selective inhibitor of p38α MAPK. It specifically blocks TNFα release.

• Description :

  P38 MAP kinase inhibitor

• Product Name Alternative :

  JNK Inhibitor XVII, BIRB796, 1-[5-tert-butyl-2- (4-methylphenyl) pyrazol-3-yl]-3-[4- (2-morpholin-4-ylethoxy) naphthalen-1-yl]urea

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥99% (HPLC)

• Weight :

  0.005

• Format :

  White solid

• Solubility :

  Soluble in DMSO

• Molecular Formula :

  C31H37N5O3

• Molecular Weight :

  527.7

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Pargellis C., et al. (2002). Nat Structural Biol. 9(4): 268–272.

• CAS Number :

  285983-48-4