Doramapimod

CAT: 0400-SIH-442-25MGSize: 25 mgDry Ice: NoHazardous: No

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CAT#:0400-SIH-442-25MGSize:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Doramapimod is a highly potent and selective inhibitor of p38α MAPK. It specifically blocks TNFα release.

Description

P38 MAP kinase inhibitor

CAS Number

285983-48-4

Product Name Alternative

JNK Inhibitor XVII, BIRB796, 1-[5-tert-butyl-2- (4-methylphenyl) pyrazol-3-yl]-3-[4- (2-morpholin-4-ylethoxy) naphthalen-1-yl]urea

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

Purity

≥99% (HPLC)

Weight

0.025

Format

White solid

Solubility

Soluble in DMSO

Molecular Formula

C31H37N5O3

Molecular Weight

527.7

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Pargellis C., et al. (2002). Nat Structural Biol. 9(4): 268–272.

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