AS 041164

• Background :

  AS 041164 is a selective PI 3-Kγ isoform inhibitor. It also blocks neutrophil migration.

• Description :

  PI 3-Kgamma kinase inhibitor

• CAS Number :

  6318-41-8

• Product Name Alternative :

  NSC31098, 5-Benzo[1,3]dioxol-5-ylmethylene-thiazolidine-2,4-dione

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥98% (TLC)

• Weight :

  0.01

• Format :

  Yellow solid

• Solubility :

  Soluble in DMSO (25 mg/ml). For in vivo administration this compound was suspended in 0.5% carboxymethylcellulose/0.25% Tween 20 as a vehicle

• Molecular Formula :

  C11H7NO4S

• Molecular Weight :

  249.2

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Ferrandi C., et al. (2007) J. Pharmacol. Exp.Ther. 322(3): 923–930.