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PHA-665752

CAT: 0400-SIH-421-5MGSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-421-5MGSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PHA 665752 is a potent and selective MET kinase, ATP-competitive inhibitor. It has been studied as an antitumor agent because it has been seen to inhibit tumorigenicity and angiogenesis in mouse lung cancer xenografts.
Description
MET kinase inhibitor
CAS Number
477575-56-7
Product Name Alternative
(2R) -1-[[5-[ (Z) -[5-[[ (2,6-Dichlorophenyl) methyl]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]methyl]-2,4-dimethyl-1H-pyrrol-3-yl]carbonyl]-2- (1-pyrrolidinylmethyl) pyrrolidine
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>98
Weight
0.005
Format
Yellow solid
Solubility
Soluble to 100 mM in DMSO.
Molecular Formula
C32H34Cl2N4O4S
Molecular Weight
641.61
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Puri N., Khramtsov A., Ahmed S., Nallasura V., Hetzel J., Jagadeeswaran R., et al. (2007) Cancer Res. 3529-34.

Alternative Products

CatalogName
A2307-5.1PHA-665752
abx076781-01PHA 665752

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