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MS-275

CAT: 0400-SIH-416-1MGSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-416-1MGSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MS 275, also referred to as Entinostat, is a benzamide histone deacetylase inhibitor. It preferentially inhibits HDAC1 and HDAC3. It is currently undergoing several clinical trials for the treatment of Hodgkin's lymphoma, advanced breast cancer, and for metastatic lung cancer.
Description
HDAC inhibitor
CAS Number
209783-80-2
Product Name Alternative
3-pyridinylmethyl [[4-[[ (2-aminophenyl) amino]carbonyl]phenyl]methyl]carbamate, N- (2-Aminophenyl) -4-[N- (pyridine-3ylmethoxycarbonyl) aminomethyl]benzamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Epigenetics and Nuclear Signaling | Cancer
Purity
>98.5
Weight
0.001
Format
Off white solid
Solubility
Soluble in DMSO or methanol.
Molecular Formula
C21H20N4O3
Molecular Weight
376.41
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Camphausen K., Burgan W., Cerra M., Oswald K.A., Trepel J.B., Lee M.J., et al. (2004) Cancer Res. 316-21.

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