Chloroquine diphosphate
CAT:
400-SIH-405-1G
Size:
1 g
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Chloroquine diphosphate
- Background: Chloroquine diphosphate was originally developed as a treatment against malaria. It has since been implicated in cancer research as it inhibits cell growth and induces cell death in a number of cancer cell lines. Chloroquine also inhibits autophagy by specifically blocking acidification of the lysosomes which fuse with autophagosomes. This consequently prevents the degradation of materials.
- Description: Autophagy inhibitor
- Product Name Alternative: N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt
- CAS Number: 50-63-5
- UNSPSC: 41116105
- Source: Synthetic
- Purity: >98% (HPLC); NMR (Conforms)
- Weight: 1
- Format: Beige Solid
- Solubility: May be dissolved in water (25mg/mL)
- Molecular Formula: C18H26ClN3·2H3PO4
- Molecular Weight: 515.86
- Precautions: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
- References & Citations: 1. Jiang P.D., et al. (2010) Biomed Pharmacother. 64(9): 609-14. 2. Egger M.E., et al. (2013) J Surg Res. 184(1): 274-81.