STF-62247

• Background:

  STF-62247 is a selective cell-permeable inducer of autophagy. This is demonstrated by an induction of large vacuole formation in cells. This observation is especially pronounced in von Hippel-Lindau deficient renal carcinoma cells. Induction of autophagy is also seen in vivo in mice.

• Description:

  Autophagy inducer

• Product Name Alternative:

  N- (3-Methylphenyl) -4- (4-pyridinyl) -2-thiazolamine

• UNSPSC:

  41116105

• Type:

  Inducer

• Source:

  Synthetic

• Field of Research:

  Cancer | Autophagy

• Purity:

  ≥98%

• Weight:

  0.01

• Format:

  Solid

• Solubility:

  Soluble in DMSO (26 mg/ml).

• Molecular Formula:

  C15H13N3S

• Molecular Weight:

  267.35

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Turcotte S., et al. (2008) Autophagy, 4(7): b944-6.

• CAS Number:

  315702-99-9