BRL-50481

• Background:

  BRL-50481 is a selective phosphodiesterase 7 (PDE7) inhibitor. In the presence of BRL-50481 the activity of hrPDE7A1 was inhibited against the phosphodiesterase (PDE3) and (PDE4) (1). Studies have suggested a potential role of BRL-50481 in the treatment of osteoporosis (2).

• Description:

  PDE7 inhibitor

• Product Name Alternative:

  N, N,2-Trimethyl-5-nitro-benzenesulfonamide

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Neuroscience

• Purity:

  >98% (TLC) ; NMR (Conforms)

• Weight:

  0.01

• Format:

  Cream solid

• Solubility:

  May be dissolved in DMSO (40 mg/ml) or Ethanol (5 mg/ml)

• Molecular Formula:

  C9H12N2O4S

• Molecular Weight:

  244.26

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Smith J., et al. (2004) Molecular Biology Pharmacology. 66(6): 1679-89. 2. Pekkinen M., et al. (2008) Bone. 43(1): 84-91.

• CAS Number:

  433695-36-4