BRL-50481

• Background :

  BRL-50481 is a selective phosphodiesterase 7 (PDE7) inhibitor. In the presence of BRL-50481 the activity of hrPDE7A1 was inhibited against the phosphodiesterase (PDE3) and (PDE4) (1). Studies have suggested a potential role of BRL-50481 in the treatment of osteoporosis (2).

• Description :

  PDE7 inhibitor

• Product Name Alternative :

  N, N,2-Trimethyl-5-nitro-benzenesulfonamide

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Neuroscience

• Purity :

  >98% (TLC) ; NMR (Conforms)

• Weight :

  0.01

• Format :

  Cream solid

• Solubility :

  May be dissolved in DMSO (40 mg/ml) or Ethanol (5 mg/ml)

• Molecular Formula :

  C9H12N2O4S

• Molecular Weight :

  244.26

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Smith J., et al. (2004) Molecular Biology Pharmacology. 66(6): 1679-89. 2. Pekkinen M., et al. (2008) Bone. 43(1): 84-91.

• CAS Number :

  433695-36-4