Kainic acid

• Background:

  Kainic acid is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. It is a central nervous system stimulant and neurotoxin. It acts as a classic neuroexcitatory agent for induction of seizures in laboratory animals (typical dose 10-30 mg/kg).

• Description:

  Kainate agonist

• Product Name Alternative:

  (2S,3S,4S) -3- (carboxymethyl) -4- (prop-1-en-2-yl) -pyrrolidine-2-carboxylic acid, Monohydrate

• UNSPSC:

  41116105

• Type:

  Agonist

• Source:

  Synthetic

• Field of Research:

  Neuroscience | Ion Channels | Neurotransmitter Receptors | Glutamate Receptors | Kainate Receptors

• Purity:

  >99% (HPLC)

• Weight:

  0.05

• Format:

  White powder

• Solubility:

  May be dissolved in water (10 mg/ml)

• Molecular Formula:

  C10H15NO4•H2O

• Molecular Weight:

  213.2

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Watkins J.C., et al. (1981) Ann. Rev. Pharmacol. Toxicol. 21: 165.

• CAS Number:

  58002-62-3