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Decitabine

CAT: 0400-SIH-352-50MGSize: 50 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-352-50MGSize:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes. Increases stem cell reprogramming efficiency. Stimulates osteogenic differentiation of human bone marrow stromal cells. Antitumor agent. Cell permeable.
Description
DNA hypomethylation agent
CAS Number
2353-33-5
Product Name Alternative
5-Aza-2'-deoxycytidine; NSC-127716, 2'-Deoxy-5-azacytidine; 4-Amino-1- (2-deoxy-β-D-erythro-pento furanosyl) -1,3,5-triazin-2 (1H) -one
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Epigenetics and Nuclear Signaling | Cancer
Purity
>98% (TLC), NMR conforms
Weight
0.05
Format
White Solid
Solubility
Soluble in 25 mg/ml DMSO, 11 mg/ml Water or Ethanol
Molecular Formula
C8H12N4O4
Molecular Weight
228.2
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Bender C.M., et al. (1998) Cancer Res. 58: 95. 2. El-Serafi A.T., et al. (2011) Differentiation 81: 35.

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